Development of a docetaxel micellar formulation using poly(ethylene glycol)-polylactide-poly(ethylene glycol) (PEG-PLA-PEG) with successful reconstitution for tumor targeted drug delivery

• Main Authors: Taehoon Sim (Author), Jae Eun Kim (Author), Ngoc Ha Hoang (Author), Jin Kook Kang (Author), Chaemin Lim (Author), Dong Shik Kim (Author), Eun Seong Lee (Author), Yu Seok Youn (Author), Han-Gon Choi (Author), Hyo-Kyung Han (Author), Kwon-Yeon Weon (Author), Kyung Taek Oh (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Docetaxel (DTX)-loaded polymeric micelles (DTBM) were formulated using the triblock copolymer, poly(ethylene glycol)-polylactide-poly(ethylene glycol) (PEG-PLA-PEG), to comprehensively study their pharmaceutical application as anticancer nanomedicine. DTBM showed a stable formulation of anticancer n...