Cross-comparison of exome analysis, next-generation sequencing of amplicons, and the iPLEX® ADME PGx Panel for pharmacogenomic profiling

Cross-comparison of exome analysis, next-generation sequencing of amplicons, and the iPLEX® ADME PGx Panel for pharmacogenomic profiling

Whole-exome sequencing (WES) has been widely used for analysis of human genetic diseases, but its value for the pharmacogenomic profiling of individuals is not well studied. Initially, we performed an in-depth evaluation of the accuracy of WES variant calling in the pharmacogenes CYP2D6 and CYP2C19...

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Main Authors: Eng Wee eChua (Author), Martin A Kennedy (Author), Simone L Cree (Author), Kim N. T. Ton (Author), Klaus eLehnert (Author), Phillip eShepherd (Author), Nuala eHelsby (Author)
Format: Book
Published: Frontiers Media S.A., 2016-01-01T00:00:00Z.
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3rd Floor Main Library

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