8-OxoG-Dependent Regulation of Global Protein Responses Leads to Mutagenesis and Stress Survival in <i>Bacillus subtilis</i>

• Main Authors: Lissett E. Martínez (Author), Gerardo Gómez (Author), Norma Ramírez (Author), Bernardo Franco (Author), Eduardo A. Robleto (Author), Mario Pedraza-Reyes (Author)
• Format: Book
• Published: MDPI AG, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The guanine oxidized (GO) system of <i>Bacillus subtilis</i>, composed of the YtkD (MutT), MutM and MutY proteins, counteracts the cytotoxic and genotoxic effects of the oxidized nucleobase 8-OxoG. Here, we report that in growing <i>B. subtilis</i> cells, the genetic inactiva...