Bupivacaine in combination with sildenafil (Viagra) and vitamin D3 have anti-inflammatory effects in osteoarthritic chondrocytes

Aims: To treat osteoarthritic chondrocytes and thereby reduce the inflammation with a drug combination that primarily affects 5-HT- and ATP-evoked Ca2+ signaling. In osteoarthritic chondrocytes, Ca2+ signaling is elevated, resulting in increased production of ATP and inflammatory mediators. The expr...

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Main Authors: Elisabeth Hansson (Author), Eva Skiöldebrand (Author)
Format: Book
Published: Elsevier, 2021-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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