Targeting HER2 Expressing Tumors with a Potent Drug Conjugate Based on an Albumin Binding Domain-Derived Affinity Protein

• Asıl Yazarlar: Javad Garousi (Yazar), Haozhong Ding (Yazar), Emma von Witting (Yazar), Tianqi Xu (Yazar), Anzhelika Vorobyeva (Yazar), Maryam Oroujeni (Yazar), Anna Orlova (Yazar), Sophia Hober (Yazar), Torbjörn Gräslund (Yazar), Vladimir Tolmachev (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2021-11-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Albumin binding domain derived affinity proteins (ADAPTs) are a class of small and folded engineered scaffold proteins that holds great promise for targeting cancer tumors. Here, we have extended the in vivo half-life of an ADAPT, targeting the human epidermal growth factor receptor 2 (HER2) by fusi...