Targeting HER2 Expressing Tumors with a Potent Drug Conjugate Based on an Albumin Binding Domain-Derived Affinity Protein

Targeting HER2 Expressing Tumors with a Potent Drug Conjugate Based on an Albumin Binding Domain-Derived Affinity Protein

Albumin binding domain derived affinity proteins (ADAPTs) are a class of small and folded engineered scaffold proteins that holds great promise for targeting cancer tumors. Here, we have extended the in vivo half-life of an ADAPT, targeting the human epidermal growth factor receptor 2 (HER2) by fusi...

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Main Authors: Javad Garousi (Author), Haozhong Ding (Author), Emma von Witting (Author), Tianqi Xu (Author), Anzhelika Vorobyeva (Author), Maryam Oroujeni (Author), Anna Orlova (Author), Sophia Hober (Author), Torbjörn Gräslund (Author), Vladimir Tolmachev (Author)
Format: Book
Published: MDPI AG, 2021-11-01T00:00:00Z.
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3rd Floor Main Library

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