CDK1 and CCNB1 as potential diagnostic markers of rhabdomyosarcoma: validation following bioinformatics analysis

• Main Authors: Qianru Li (Author), Liang Zhang (Author), Jinfang Jiang (Author), Yangyang Zhang (Author), Xiaomeng Wang (Author), Qiaochu Zhang (Author), Yang Wang (Author), Chunxia Liu (Author), Feng Li (Author)
• Format: Book
• Published: BMC, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Rhabdomyosarcoma (RMS), a common soft-tissue malignancy in pediatrics, presents high invasiveness and mortality. However, besides known changes in the PAX3/7-FOXO1 fusion gene in alveolar RMS, the molecular mechanisms of the disease remain incompletely understood. The purpose of...