Lovastatin Alleviates Endothelial-to-Mesenchymal Transition in Glomeruli via Suppression of Oxidative Stress and TGF-β1 Signaling

• Main Authors: Zejun Ma (Author), Lili Zhu (Author), Yan Liu (Author), Zhida Wang (Author), Yang Yang (Author), Liming Chen (Author), Qiulun Lu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Statins may decrease chronic kidney diseases (CKDs) risk, but their underlying molecular mechanisms are not completely understood. Recent studies indicate Endothelial-to-mesenchymal transition (EndMT) plays an important role contributing to renal interstitial fibrosis. In the present study, we first...