Dual-ligand modified liposomes provide effective local targeted delivery of lung-cancer drug by antibody and tumor lineage-homing cell-penetrating peptide

• Main Authors: Congcong Lin (Author), Xue Zhang (Author), Hubiao Chen (Author), Zhaoxiang Bian (Author), Ge Zhang (Author), Muhammad Kashif Riaz (Author), Deependra Tyagi (Author), Ge Lin (Author), Yanbo Zhang (Author), Jinjin Wang (Author), Aiping Lu (Author), Zhijun Yang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The abilities of a drug delivery system to target and penetrate tumor masses are key factors in determining the system's chemotherapeutic efficacy. Here, we explored the utility of an anti-carbonic anhydrase IX (anti-CA IX) antibody and CPP33 dual-ligand modified triptolide-loaded liposomes (dl...