Pharmaceutical Approach to Develop Novel Photosensitizer Nanoformulation: An Example of Design and Characterization Rationale of Chlorophyll α Derivative

• Main Authors: Maria B. Sokol (Author), Veronika A. Beganovskaya (Author), Mariia R. Mollaeva (Author), Nikita G. Yabbarov (Author), Margarita V. Chirkina (Author), Dmitry V. Belykh (Author), Olga M. Startseva (Author), Anton E. Egorov (Author), Alexey A. Kostyukov (Author), Vladimir A. Kuzmin (Author), Sergei M. Lomakin (Author), Natalia G. Shilkina (Author), Alexey V. Krivandin (Author), Olga V. Shatalova (Author), Margarita A. Gradova (Author), Maxim A. Abakumov (Author), Aleksey A. Nikitin (Author), Varvara P. Maksimova (Author), Kirill I. Kirsanov (Author), Elena D. Nikolskaya (Author)
• Format: Book
• Published: MDPI AG, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this study, we described physico-chemical properties of novel nanoformulation of photosensitizer-pyropheophorbide α 17-diethylene glycol ester (XL) (chlorophyll α derivative), revealing insights into antitumor activity and maintaining quality, meeting the pharmaceutical approach of new nanoformul...