The Identification of Novel CYP2D6 Variants in US Hmong: Results From Genome Sequencing and Clinical Genotyping

• Principais autores: Ya Feng Wen (Autor), Andrea Gaedigk (Autor), Erin C. Boone (Autor), Wendy Y. Wang (Autor), Robert J. Straka (Autor)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Objective: Hmong individuals represent a unique East Asian subpopulation in whom limited information concerning pharmacogenetic variation exists. The objectives of this study were to comprehensively characterize the highly polymorphic CYP2D6 gene in Hmong, estimate allele and phenotype frequencies a...