Atractylenolide I ameliorates cancer cachexia through inhibiting biogenesis of IL‐6 and tumour‐derived extracellular vesicles

• Main Authors: Meng Fan (Author), Xiaofan Gu (Author), Wanli Zhang (Author), Qiang Shen (Author), Ruiqin Zhang (Author), Qiaoyu Fang (Author), Yueping Wang (Author), Xiaodong Guo (Author), Xiongwen Zhang (Author), Xuan Liu (Author)
• Format: Book
• Published: Wiley, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Atractylenolide I (AI) is a natural sesquiterpene lactone isolated from Atractylodes macrocephala Koidz, known as Baizhu in traditional Chinese medicine. AI has been found to ameliorate cancer cachexia in clinic cancer patients and in tumour‐bearing mice. Here, we checked the inf...