DESIGN AND OPTIMIZATION OF SOLID LIPID NANOPARTICLES (SLNs) OF ZOLMITRIPTAN FOR THE MANAGEMENT OF MIGRAINE
Solid lipid nanoparticles (SLNs) of zolmitriptan were produced by solvent emulsification-diffusion technique. Soya lecithin and poloxamer 188 were used as surfactants and stabilizers of the particles. The formulations were optimized for independent variables (amount of stearic acid, amount of lecith...
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Universitas Gadjah Mada,
2013-10-01T00:00:00Z.
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