Partial promoter substitutions generating transcriptional sentinels of diverse signaling pathways in embryonic stem cells and mice

• Main Authors: Palle Serup (Author), Carsten Gustavsen (Author), Tino Klein (Author), Leah A. Potter (Author), Robert Lin (Author), Nandita Mullapudi (Author), Ewa Wandzioch (Author), Angela Hines (Author), Ashley Davis (Author), Christine Bruun (Author), Nina Engberg (Author), Dorthe R. Petersen (Author), Janny M. L. Peterslund (Author), Raymond J. MacDonald (Author), Anne Grapin-Botton (Author), Mark A. Magnuson (Author), Kenneth S. Zaret (Author)
• Format: Book
• Published: The Company of Biologists, 2012-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

SUMMARY Extracellular signals in development, physiology, homeostasis and disease often act by regulating transcription. Herein we describe a general method and specific resources for determining where and when such signaling occurs in live animals and for systematically comparing the timing and ext...