Tailoring Apixaban in Nanostructured Lipid Carrier Enhancing Its Oral Bioavailability and Anticoagulant Activity

Tailoring Apixaban in Nanostructured Lipid Carrier Enhancing Its Oral Bioavailability and Anticoagulant Activity

Apixaban (Apx), an oral anticoagulant drug, is a direct factor Xa inhibitor for the prophylaxis against venous thromboembolism. Apx has limited oral bioavailability and poor water solubility. The goal of this study was to improve the formulation of an Apx-loaded nanostructured lipid carrier (NLC) to...

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Main Authors: Mohamed F. Zaky (Author), Mohamed A. Megahed (Author), Taha M. Hammady (Author), Shadeed Gad (Author), Mamdouh Mostafa Ghorab (Author), Khalid M. El-Say (Author)
Format: Book
Published: MDPI AG, 2022-12-01T00:00:00Z.
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