N-thioalkylcarbazoles derivatives as new anti-proliferative agents: synthesis, characterisation and molecular mechanism evaluation

• Principais autores: Maria Stefania Sinicropi (Autor), Domenico Iacopetta (Autor), Camillo Rosano (Autor), Rosario Randino (Autor), Anna Caruso (Autor), Carmela Saturnino (Autor), Noemi Muià (Autor), Jessica Ceramella (Autor), Francesco Puoci (Autor), Manuela Rodriquez (Autor), Pasquale Longo (Autor), Maria Rosaria Plutino (Autor)
• Formato: Livro
• Publicado em: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Synthetic or natural carbazole derivatives constitute an interesting class of heterocycles, which showed several pharmaceutical properties and occupied a promising place as antitumour tools in preclinical studies. They target several cellular key-points, e.g. DNA and Topoisomerases I and II. The mos...