The Protective Role of Bioactive Quinones in Stress-induced Senescence Phenotype of Endothelial Cells Exposed to Cigarette Smoke Extract

• Main Authors: Ilenia Cirilli (Author), Patrick Orlando (Author), Fabio Marcheggiani (Author), Phiwayinkosi V. Dludla (Author), Sonia Silvestri (Author), Elisabetta Damiani (Author), Luca Tiano (Author)
• Format: Book
• Published: MDPI AG, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Endothelial dysfunction represents the initial stage in atherosclerotic lesion development which occurs physiologically during aging, but external factors like diet, sedentary lifestyle, smoking accelerate it. Since cigarette smoking promotes oxidative stress and cell damage, we developed an in vitr...