Tumor microenvironment and cancer metastasis: molecular mechanisms and therapeutic implications

• Main Authors: Cigir Biray Avci (Author), Bakiye Goker Bagca (Author), Masoud Nikanfar (Author), Leila Sabour Takanlou (Author), Maryam Sabour Takanlou (Author), Alireza Nourazarian (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The tumor microenvironment (TME) plays a crucial role in cancer development and metastasis. This review summarizes the current research on how the TME promotes metastasis through molecular pathways, focusing on key components, such as cancer-associated fibroblasts, immune cells, endothelial cells, c...