Production and Characterization of Chitosan-Polyanion Nanoparticles by Polyelectrolyte Complexation Assisted by High-Intensity Sonication for the Modified Release of Methotrexate

• Главные авторы: Yhors Ciro (Автор), John Rojas (Автор), Maria J. Alhajj (Автор), Gustavo A. Carabali (Автор), Constain H. Salamanca (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2020-01-01T00:00:00Z.
• Предметы: article
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A promising strategy to improve the effectivity of anticancer treatment and decrease its side effects is to modulate drug release by using nanoparticulates (NPs) as carriers. In this study, methotrexate-loaded chitosan−polyanion nanoparticles were produced by polyelectrolyte complexation a...