Production and Characterization of Chitosan-Polyanion Nanoparticles by Polyelectrolyte Complexation Assisted by High-Intensity Sonication for the Modified Release of Methotrexate

• Päätekijät: Yhors Ciro (Tekijä), John Rojas (Tekijä), Maria J. Alhajj (Tekijä), Gustavo A. Carabali (Tekijä), Constain H. Salamanca (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2020-01-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

A promising strategy to improve the effectivity of anticancer treatment and decrease its side effects is to modulate drug release by using nanoparticulates (NPs) as carriers. In this study, methotrexate-loaded chitosan−polyanion nanoparticles were produced by polyelectrolyte complexation a...