Production and Characterization of Chitosan-Polyanion Nanoparticles by Polyelectrolyte Complexation Assisted by High-Intensity Sonication for the Modified Release of Methotrexate

• Autores principales: Yhors Ciro (Autor), John Rojas (Autor), Maria J. Alhajj (Autor), Gustavo A. Carabali (Autor), Constain H. Salamanca (Autor)
• Formato: Libro
• Publicado: MDPI AG, 2020-01-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

A promising strategy to improve the effectivity of anticancer treatment and decrease its side effects is to modulate drug release by using nanoparticulates (NPs) as carriers. In this study, methotrexate-loaded chitosan−polyanion nanoparticles were produced by polyelectrolyte complexation a...