Stem cell‐derived extracellular vesicles reduce the expression of molecules involved in cardiac hypertrophy-In a model of human-induced pluripotent stem cell-derived cardiomyocytes

• Main Authors: Alina Constantin (Author), Ioana Karla Comarița (Author), Nicoleta Alexandru (Author), Alexandru Filippi (Author), Florina Bojin (Author), Mihaela Gherghiceanu (Author), Alexandra Vîlcu (Author), Miruna Nemecz (Author), Loredan Stefan Niculescu (Author), Virgil Păunescu (Author), Adriana Georgescu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cardiac pathological hypertrophy is the major risk factor that usually progresses to heart failure. We hypothesized that extracellular vesicles (EVs), known to act as important mediators in regulating physiological and pathological functions, could have the potential to reduce the cardiac hypertroph...