Drug-Drug Interactions and Pharmacogenomic Evaluation in Colorectal Cancer Patients: The New Drug-PIN^® System Comprehensive Approach

• Main Authors: Michela Roberto (Author), Alessandro Rossi (Author), Martina Panebianco (Author), Leda Marina Pomes (Author), Giulia Arrivi (Author), Debora Ierinò (Author), Maurizio Simmaco (Author), Paolo Marchetti (Author), Federica Mazzuca (Author)
• Format: Book
• Published: MDPI AG, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Drug-drug interactions (DDIs) can affect both treatment efficacy and toxicity. We used Drug-PIN^® (Personalized Interactions Network) software in colorectal cancer (CRC) patients to evaluate drug-drug-gene interactions (DDGIs), defined as the combination of DDIs and individual...