Farnesyl diphosphate synthase regulated endothelial proliferation and autophagy during rat pulmonary arterial hypertension induced by monocrotaline

• Main Authors: Tingting Jin (Author), Jiangting Lu (Author), Qingbo Lv (Author), Yingchao Gong (Author), Zhaojin Feng (Author), Hangying Ying (Author), Meihui Wang (Author), Guosheng Fu (Author), Dongmei Jiang (Author)
• Format: Book
• Published: BMC, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The proliferation ability and autophagy level of pulmonary artery endothelial cells (PAECs) play an important role in promoting the development of pulmonary artery hypertension (PAH), and there is still no effective treatment for PAH. Farnesyl diphosphate synthase (FDPS) is a key...