Long-Term Use of Amoxicillin Is Associated with Changes in Gene Expression and DNA Methylation in Patients with Low Back Pain and Modic Changes

• Príomhchruthaitheoirí: Maria Dehli Vigeland (Údar), Siri Tennebø Flåm (Údar), Magnus Dehli Vigeland (Údar), Ansgar Espeland (Údar), Manuela Zucknick (Údar), Monica Wigemyr (Údar), Lars Christian Haugli Bråten (Údar), Elisabeth Gjefsen (Údar), John-Anker Zwart (Údar), Kjersti Storheim (Údar), Linda Margareth Pedersen (Údar), Kaja Selmer (Údar), Benedicte Alexandra Lie (Údar), Kristina Gervin (Údar), The AIM Study Group (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: MDPI AG, 2023-07-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Long-term antibiotics are prescribed for a variety of medical conditions, recently including low back pain with Modic changes. The molecular impact of such treatment is unknown. We conducted longitudinal transcriptome and epigenome analyses in patients (<i>n</i> = 100) receiving amoxicil...