Apply a Physiologically Based Pharmacokinetic Model to Promote the Development of Enrofloxacin Granules: Predict Withdrawal Interval and Toxicity Dose

• Main Authors: Kaixiang Zhou (Author), Aimei Liu (Author), Wenjin Ma (Author), Lei Sun (Author), Kun Mi (Author), Xiangyue Xu (Author), Samah Attia Algharib (Author), Shuyu Xie (Author), Lingli Huang (Author)
• Format: Book
• Published: MDPI AG, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Enrofloxacin (ENR) granules were developed to prevent and control the infections caused by foodborne zoonotic intestinal pathogens in our previous studies. To promote the further development of ENR granules and standardize their usage in pigs, a physiologically based pharmacokinetic (PBPK) model of...