Identification, synthesis and characterization of an unknown process related impurity in eslicarbazepine acetate active pharmaceutical ingredient by LC/ESIâIT/MS, 1H, 13C and 1Hâ1H COSY NMR

• Main Authors: Saji Thomas (Author), Saroj Kumar Paul (Author), Subhash Chandra Joshi (Author), Vineet Kumar (Author), Ashutosh Agarwal (Author), Dharam Vir (Author)
• Format: Book
• Published: Elsevier, 2014-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A new impurity was detected during high performance liquid chromatographic (HPLC) analysis of eslicarbazepine acetate active pharmaceutical ingredient. The structure of unknown impurity was postulated based on liquid chromatography mass spectrometry using electrospray ionization and ion trap analyze...