Cell-free fetal DNA testing and its correlation with prenatal indications

• Main Authors: Jing-wei Wang (Author), Yong-nan Lyu (Author), Bin Qiao (Author), Yan Li (Author), Yan Zhang (Author), Pavan Kumar Dhanyamraju (Author), Yevgeniya Bamme (Author), Michael D. Yu (Author), Dongqin Yang (Author), Yong-qing Tong (Author)
• Format: Book
• Published: BMC, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Highlights The whole-genome sequencing of cell-free fetal DNA from maternal plasma is an effective prenatal screening tool for pregnancies with various prenatal indications. The concentration of cffDNA was linear with gestational age and the Z-score values of the positive NIPT group. NIPT has a sign...