E-Cadherin expression in human tumors: a tissue microarray study on 10,851 tumors

• Main Authors: Eike Burandt (Author), Felix Lübbersmeyer (Author), Natalia Gorbokon (Author), Franziska Büscheck (Author), Andreas M. Luebke (Author), Anne Menz (Author), Martina Kluth (Author), Claudia Hube-Magg (Author), Andrea Hinsch (Author), Doris Höflmayer (Author), Sören Weidemann (Author), Christoph Fraune (Author), Katharina Möller (Author), Frank Jacobsen (Author), Patrick Lebok (Author), Till Sebastian Clauditz (Author), Guido Sauter (Author), Ronald Simon (Author), Ria Uhlig (Author), Waldemar Wilczak (Author), Stefan Steurer (Author), Sarah Minner (Author), Rainer Krech (Author), David Dum (Author), Till Krech (Author), Andreas Holger Marx (Author), Christian Bernreuther (Author)
• Format: Book
• Published: BMC, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The E-Cadherin gene (CDH1, Cadherin 1), located at 16q22.1 encodes for a calcium-dependent membranous glycoprotein with an important role in cellular adhesion and polarity maintenance. Methods To systematically determine E-Cadherin protein expression in normal and cancerous tissu...