Nano-hesperetin ameliorates 6-hydroxydopamine-induced behavioral deficits and oxidative damage by up-regulating gene expression of antioxidant enzymes

• Main Authors: Akbar Hajizadeh Moghaddam (Author), Sara Alizadeh (Author), Monireh Nejadi (Author), Seyed Reza Mokhtari Sangdehi (Author), Mahboobeh Zare (Author), Mojtaba Ranjbar (Author)
• Format: Book
• Published: Mashhad University of Medical Sciences, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Hesperetin (Hst) has shown several pharmacological effects. The efficacy of Hst is highly restricted in vivo due mainly to poor bioavailability. This investigation was intended to compare the influence of Hst and nano-Hst treatment on 6-hydroxydopamine (6-OHDA)-induced behavioral deficits...