Prospective monitoring of chronic myeloid leukemia patients from the time of TKI discontinuation: the fate of peripheral blood CD26+ leukemia stem cells

• Main Authors: Paola Pacelli (Author), Adele Santoni (Author), Anna Sicuranza (Author), Elisabetta Abruzzese (Author), Valentina Giai (Author), Monica Crugnola (Author), Mario Annunziata (Author), Sara Galimberti (Author), Alessandra Iurlo (Author), Luigiana Luciano (Author), Federica Sorà (Author), Carmen Fava (Author), Elena Bestoso (Author), Cristina Marzano (Author), Alessandra Cartocci (Author), Marzia Defina (Author), Vincenzo Sammartano (Author), Emanuele Cencini (Author), Donatella Raspadori (Author), Monica Bocchia (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: In chronic myeloid leukemia (CML), about half of the patients achieving a deep and stable molecular response with tyrosine kinase inhibitors (TKIs) may discontinue TKI treatment without disease recurrence. As such, treatment-free remission (TFR) has become an ambitious goal of treatmen...