Effects of urotensin II receptor antagonist, GSK1440115, in asthma

• 主要な著者: Alison D Portnoy (著者), Sanjay eKumar (著者), David J Behm (著者), Kelly M Mahr (著者), Robert B Noble (著者), John eThroup (著者), Steven F Russ (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2013-04-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Background: Urotensin II (U-II) is highly expressed in the human lung and has been implicated in regulating respiratory physiology in preclinical studies. Our objective was to test antagonism of the urotensin receptor (UT) by GSK1440115, a novel, competitive and selective inhibitor of the UT recepto...