Pre-cART Immune Parameters in People Living With HIV Might Help Predict CD8+ T-Cell Characteristics, Inflammation Levels, and Reservoir Composition After Effective cART

• Main Authors: Jimena Salido (Author), Alejandro Czernikier (Author), Cesar Trifone (Author), María Laura Polo (Author), María Ines Figueroa (Author), Alejandra Urioste (Author), Pedro Cahn (Author), Omar Sued (Author), Horacio Salomon (Author), Natalia Laufer (Author), Yanina Ghiglione (Author), Gabriela Turk (Author)
• Format: Book
• Published: Case Western Reserve University, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Combined antiretroviral treatment (cART) for HIV infection is highly effective in controlling viral replication. However, it cannot achieve a sterilizing cure.  Several strategies have been proposed to achieve a functional cure, some of them based on immune-mediated clearing of persisten...