Classification of human cancers based on DNA copy number amplification modeling

• Main Authors: Knuutila Sakari (Author), Böhling Tom (Author), Tikka Jarkko (Author), Myllykangas Samuel (Author), Hollmén Jaakko (Author)
• Format: Book
• Published: BMC, 2008-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>DNA amplifications alter gene dosage in cancer genomes by multiplying the gene copy number. Amplifications are quintessential in a considerable number of advanced cancers of various anatomical locations. The aims of this study were t...