Hypoglycemic Activity and the Potential Mechanism of the Flavonoid Rich Extract from Sophora tonkinensis Gagnep. in KK-Ay Mice

• Prif Awduron: Mi Huang (Awdur), Shihao Deng (Awdur), Qianqian Han (Awdur), Ping Zhao (Awdur), Qi Zhou (Awdur), Sijian Zheng (Awdur), Xinhua Ma (Awdur), Chan Xu (Awdur), Jing Yang (Awdur), Xinzhou Yang (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Frontiers Media S.A., 2016-09-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

This study investigated the active principles, hypoglycemic activity and potential mechanisms of the flavonoid rich extract from Sophora tonkinensis Gagnep. (SS-EtOAc) in KK-Ay diabetic mice. An off-line semipreparative LC-NMR and LC-UV-ESIMS protocol was performed to determine 13 flavonoids from SS...