Hypoglycemic Activity and the Potential Mechanism of the Flavonoid Rich Extract from Sophora tonkinensis Gagnep. in KK-Ay Mice

• Main Authors: Mi Huang (Author), Shihao Deng (Author), Qianqian Han (Author), Ping Zhao (Author), Qi Zhou (Author), Sijian Zheng (Author), Xinhua Ma (Author), Chan Xu (Author), Jing Yang (Author), Xinzhou Yang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study investigated the active principles, hypoglycemic activity and potential mechanisms of the flavonoid rich extract from Sophora tonkinensis Gagnep. (SS-EtOAc) in KK-Ay diabetic mice. An off-line semipreparative LC-NMR and LC-UV-ESIMS protocol was performed to determine 13 flavonoids from SS...