A Flavonoid-Rich Extract of Mandarin Juice Counteracts 6-OHDA-Induced Oxidative Stress in SH-SY5Y Cells and Modulates Parkinson-Related Genes

• Main Authors: Santa Cirmi (Author), Alessandro Maugeri (Author), Giovanni Enrico Lombardo (Author), Caterina Russo (Author), Laura Musumeci (Author), Sebastiano Gangemi (Author), Gioacchino Calapai (Author), Davide Barreca (Author), Michele Navarra (Author)
• Format: Book
• Published: MDPI AG, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Parkinson's disease (PD) is a degenerative disorder of the nervous system due to unceasing impairment of dopaminergic neurons situated in the substantia nigra. At present, anti-PD drugs acting on dopamine receptors are mainly symptomatic and have only very limited neuroprotective effects, where...