PCSK9 Expression in Epicardial Adipose Tissue: Molecular Association with Local Tissue Inflammation

• Main Authors: Elena Dozio (Author), Massimiliano Ruscica (Author), Elena Vianello (Author), Chiara Macchi (Author), Clementina Sitzia (Author), Gerd Schmitz (Author), Lorenza Tacchini (Author), Massimiliano M. Corsi Romanelli (Author)
• Format: Book
• Published: Hindawi Limited, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Epicardial adipose tissue (EAT) has the unique property to release mediators that nourish the heart in healthy conditions, an effect that becomes detrimental when volume expands and proinflammatory cytokines start to be produced. Proprotein convertase subtilisin/kexin type 9 (PCSK9), a proinflammato...