T22-PE24-H6 Nanotoxin Selectively Kills CXCR4-High Expressing AML Patient Cells In Vitro and Potently Blocks Dissemination In Vivo

• প্রধান লেখক: Yáiza Núñez (লেখক), Annabel Garcia-León (লেখক), Aïda Falgàs (লেখক), Naroa Serna (লেখক), Laura Sánchez-García (লেখক), Ana Garrido (লেখক), Jorge Sierra (লেখক), Alberto Gallardo (লেখক), Ugutz Unzueta (লেখক), Esther Vázquez (লেখক), Antonio Villaverde (লেখক), Ramon Mangues (লেখক), Isolda Casanova (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2023-02-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Despite advances in the development of targeted therapies for acute myeloid leukemia (AML), most patients relapse. For that reason, it is still necessary to develop novel therapies that improve treatment effectiveness and overcome drug resistance. We developed T22-PE24-H6, a protein nanoparticle tha...