Yeast-model-based study identified myosin- and calcium-dependent calmodulin signalling as a potential target for drug intervention in chorea-acanthocytosis
Chorea-acanthocytosis (ChAc) is a rare neurodegenerative disease associated with mutations in the human VPS13A gene. The mechanism of ChAc pathogenesis is unclear. A simple yeast model was used to investigate the function of the single yeast VSP13 orthologue, Vps13. Vps13, like human VPS13A, is invo...
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| Main Authors: | , , , , , , |
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| Format: | Book |
| Published: |
The Company of Biologists,
2019-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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