Endogenous CCN5 Participates in Angiotensin II/TGF-β1 Networking of Cardiac Fibrosis in High Angiotensin II-Induced Hypertensive Heart Failure

Endogenous CCN5 Participates in Angiotensin II/TGF-β1 Networking of Cardiac Fibrosis in High Angiotensin II-Induced Hypertensive Heart Failure

Aberrant activation of angiotensin II (Ang II) accelerates hypertensive heart failure (HF); this has drawn worldwide attention. The complex Ang II/transforming growth factor (TGF)-β1 networking consists of central mechanisms underlying pro-fibrotic effects; however, this networking still remains unc...

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Main Authors: Anan Huang (Author), Huihui Li (Author), Chao Zeng (Author), Wanli Chen (Author), Liping Wei (Author), Yue Liu (Author), Xin Qi (Author)
Format: Book
Published: Frontiers Media S.A., 2020-09-01T00:00:00Z.
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