Model‐Based Prediction of Plasma Concentration and Enterohepatic Circulation of Total Bile Acids in Humans

• Autores principales: Benjamin Guiastrennec (Autor), David P. Sonne (Autor), Martin Bergstrand (Autor), Tina Vilsbøll (Autor), Filip K. Knop (Autor), Mats O. Karlsson (Autor)
• Formato: Libro
• Publicado: Wiley, 2018-09-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Bile acids released postprandially can modify the rate and extent of lipophilic compounds' absorption. This study aimed to predict the enterohepatic circulation (EHC) of total bile acids (TBAs) in response to caloric intake from their spillover in plasma. A model for TBA EHC was combined with a...