A Case of Methotrexate Neurotoxicity Presented as Status Epilepticus, Encephalopathy, and High Fever

• Main Authors: Itay Ayalon MD (Author), Shirley Friedman MD (Author), Yoav Binenbaum MD (Author), Noga Oppenheimer MD (Author), Shelly Shiran MD (Author), Galia Grisaru-Soen MD (Author), Shimrit Uliel-Sibony MD (Author), Miguel Glatstein MD (Author), Jennifer Melissa Kaplan MD, MS (Author), Efraim Sadot MD (Author)
• Formato: Libro
• Publicado: SAGE Publishing, 2019-07-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

High-dose methotrexate is used to treat a range of adult and childhood cancers including osteosarcoma. Significant neurotoxicity is reported in 1% to 4.5% of patients treated with high-dose methotrexate and can present in a wide variety of symptoms. We present a case of a 14-year-old boy with a rece...