Unveiling the oral-gut connection: chronic apical periodontitis accelerates atherosclerosis via gut microbiota dysbiosis and altered metabolites in apoE−/− Mice on a high-fat diet

• Main Authors: Guowu Gan (Author), Shihan Lin (Author), Yufang Luo (Author), Yu Zeng (Author), Beibei Lu (Author), Ren Zhang (Author), Shuai Chen (Author), Huaxiang Lei (Author), Zhiyu Cai (Author), Xiaojing Huang (Author)
• Format: Book
• Published: Nature Publishing Group, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The aim of this study was to explore the impact of chronic apical periodontitis (CAP) on atherosclerosis in apoE−/− mice fed high-fat diet (HFD). This investigation focused on the gut microbiota, metabolites, and intestinal barrier function to uncover potential links between oral health and...