Population Pharmacokinetics of Caspofungin and Dosing Optimization in Children With Allogeneic Hematopoietic Stem Cell Transplantation

• Main Authors: Chang-He Niu (Author), Hua Xu (Author), Liu-Liu Gao (Author), Ying-Ming Nie (Author), Li-Peng Xing (Author), Li-Peng Yu (Author), San-Lan Wu (Author), Yang Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Caspofungin is the first echinocandin antifungal agent that licented for pediatric use in invasive candidiasis and aspergillosis. In this study, we evaluated the population pharmacokinetics of caspofungin and investigate appropriate dosing optimization against Candida spp. in children with allogenei...