Spray-Dried Paracetamol/Polyvinylpyrrolidone Amorphous Solid Dispersions: Part I-Stability of Powders and Tablets

• मुख्य लेखकों: Lena Ritters (लेखक), Yuanyuan Tian (लेखक), Stephan Reichl (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2021-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The formulation of active pharmaceutical ingredients (APIs) in amorphous solid dispersions (ASDs) is a promising approach to improve the bioavailability of poorly soluble compounds. However, problems often arise in the production of tablets from ASDs regarding the compressibility and recrystallizati...