Tissue expression of retinoic acid receptor alpha and CRABP2 in metastatic nephroblastomas

• Main Authors: Ana Paula Percicote (Author), Gabriel Lazaretti Mardegan (Author), Elizabeth Schneider Gugelmim (Author), Sergio Ossamu Ioshii (Author), Ana Paula Kuczynski (Author), Seigo Nagashima (Author), Lúcia de Noronha (Author)
• Format: Book
• Published: BMC, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Nephroblastoma or Wilms tumor is the most frequent kidney cancer in children and accounts for 98% of kidney tumors in this age group. Despite favorable prognosis, a subgroup of these patients progresses to recurrence and death. The retinoic acid (RA) pathway plays a role in the c...