Aryl-hydrocarbon receptor binding and the incidence of type 2 diabetes: the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)

• Main Authors: Bruce B. Duncan (Author), Cristina D. Castilhos (Author), Paula A. Bracco (Author), Maria I. Schmidt (Author), Sora Kang (Author), Suyeol Im (Author), Hong-Kyu Lee (Author), Álvaro Vigo (Author), Youngmi K. Pak (Author)
• Format: Book
• Published: BMC, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Persistent organic pollutants (POPs) may cause diabetes, in part through aryl hydrocarbon receptor (AhR) binding. Ensuing mitochondrial dysfunction is postulated to mediate this effect. We aim to investigate the association of POPs with incident diabetes indirectly by bio-assayin...