Tumor necrosis factor-α enhances the expression of vascular endothelial growth factor in a mouse orthodontic tooth movement model

• Main Authors: Takahiro Noguchi (Author), Hideki Kitaura (Author), Aseel Marahleh (Author), Fumitoshi Ohori (Author), Yasuhiko Nara (Author), Adya Pramusita (Author), Ria Kinjo (Author), Jinghan Ma (Author), Kayoko Kanou (Author), Itaru Mizoguchi (Author)
• Format: Book
• Published: Elsevier, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/purpose: Tooth movement that is achieved using orthodontic mechanical principles relies on bone resorption which takes place on the compression side via osteoclasts. Tumor necrosis factor-α (TNF-α) has been known to affect osteoclast formation in orthodontic tooth movement (OTM). Vascular...