Medicinal attributes of pyrazolo[1,5-a]pyrimidine based scaffold derivatives targeting kinases as anticancer agents

• Ngā kaituhi matua: Nasser S.M. Ismail (Author), Ghada M.E. Ali (Author), Diaa A. Ibrahim (Author), Amira M. Elmetwali (Author)
• Hōputu: Pukapuka
• I whakaputaina: SpringerOpen, 2016-12-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Pyrazolo pyrimidines are fused heterocyclic ring systems which known as bioisosteres of adenine, that are necessary for every aspect of cell life. Pyrazolo[1,5-a]pyrimidines derivatives have been explored for their inhibitory activity towards a variety of protein kinase enzymes and their function as...