Hepatoprotective activity of QBD-based optimized N-acetyl cysteine solid lipid nanoparticles against CCL4-induced liver injury in mice

• Main Authors: Bhavana Madupoju (Author), Subhakar Raju Rapaka (Author), Narender Malothu (Author), Prasanna Kumar Desu (Author), Ankarao Areti (Author)
• Format: Knjiga
• Izdano: Pensoft Publishers, 2023-11-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Purpose: In the present study, N-acetyl cysteine (NAC)-Solid Lipid Nanoparticles (SLNs) were developed employing the Quality by Design (QBD) approach for the application of hepatoprotective activity. Methods: Using Box-Behnken Design (BBD) three independent variables (Soya lecithin, polysorbate cont...