Imidazole-based phenanthroline derivatives induce DNA damage-mediated apoptosis to suppress hepatocellular carcinoma

• Main Authors: Jie LIN (Author), Shuyuan ZHOU (Author), Hairong XIAN (Author), Weiming CHEN (Author), Yifan ZHANG (Author), Weiwei ZHANG (Author), Zhihong GUAN (Author), Wenjie MEI (Author)
• Format: Book
• Published: KeAi Communications Co., Ltd., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: This study focused on designing and subsequently screening novel phenanthroimidazole derivatives with activity as potential inhibitors of hepatocellular carcinoma. Methods: We synthesized a series of phenanthroimidazole derivatives and their molecular structures were characterized by ESI-...