Prediction of the Drug-Drug Interaction Potential between Tegoprazan and Amoxicillin/Clarithromycin Using the Physiologically Based Pharmacokinetic and Pharmacodynamic Model

Tegoprazan is a novel potassium-competitive acid blocker. This study investigated the effect of drug-drug interaction on the pharmacokinetics and pharmacodynamics of tegoprazan co-administered with amoxicillin and clarithromycin, the first-line therapy for the eradication of <i>Helicobacter py...

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Hoofdauteurs: Zhuodu Wei (Auteur), Hyeon-Cheol Jeong (Auteur), Min-Gul Kim (Auteur), Kwang-Hee Shin (Auteur)
Formaat: Boek
Gepubliceerd in: MDPI AG, 2023-02-01T00:00:00Z.
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