Epimedin A inhibits the PI3K/AKT/NF-κB signalling axis and osteoclast differentiation by negatively regulating TRAF6 expression

• Egile Nagusiak: Jun Li (Egilea), Jia J. Wei (Egilea), Cen H. Wu (Egilea), Tao Zou (Egilea), Hong Zhao (Egilea), Tian Q. Huo (Egilea), Cheng J. Wei (Egilea), Ting Yang (Egilea)
• Formatua: Liburua
• Argitaratua: BMC, 2024-08-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Abstract Background Epimedin A (EA) has been shown to suppress extensive osteoclastogenesis and bone resorption, but the effects of EA remain incompletely understood. The aim of our study was to investigate the effects of EA on osteoclastogenesis and bone resorption to explore the corresponding sign...